klimkina wrote:И что, есть clinical studies, которые подтверждают что статины улучшают артерии?
Я не знаю, как проверить, что они улучшают артерии. Есть клинические исследования, показывающие, что они уменьшают частоту инфарктов и смертность от сердечно-сосудистых заболеваний.
Вот, к примеру.
Health Technol Assess. 2007 Apr;11(14):1-160, iii-iv.
A systematic review and economic evaluation of statins for the prevention of coronary events.
Ward S, Lloyd Jones M, Pandor A, Holmes M, Ara R, Ryan A, Yeo W, Payne N.
Thirty-one randomised studies were identified that compared a statin with placebo or with another statin, and reported clinical outcomes. Meta-analysis of the available data from the placebo-controlled studies indicates that, in patients with, or at risk of, CVD, statin therapy is associated with a reduced relative risk of all cause mortality, cardiovascular mortality, CHD mortality and fatal myocardial infarction (MI), but not of fatal stroke. It is also associated with a reduced relative risk of morbidity [non-fatal stroke, non-fatal MI, transient ischaemic attack (TIA), unstable angina] and of coronary revascularisation.
Prev Cardiol. 2010 Spring;13(2):84-90.
Statins for primary prevention of cardiovascular mortality in women: a systematic review and meta-analysis.
Bukkapatnam RN, Gabler NB, Lewis WR.
Division of Cardiovascular Medicine, University of California, Davis Medical Center, Sacramento, CA, USA.
Abstract
The benefits of statins on prevention of coronary heart disease in women without heart disease have not been clarified. The authors systematically reviewed all the published literature on primary prevention trials and found 6 primary prevention trials to date with sex-specific data on mortality and coronary heart disease events in women. The summary risk ratio for primary prevention of all-cause mortality was 0.90 (95% confidence interval, 0.60-1.35; P=.61) and for any coronary heart disease event was 0.78 (95% confidence interval, 0.64-0.96; P=.02). This review reveals that statin therapy along with diet and exercise in moderately hyperlipidemic women without a previous history of cardiovascular disease is of significant benefit in preventing coronary heart disease events but of no proven benefit in preventing all-cause mortality.
Это, конечно, не повод бросаться есть статины вместо рыбьего жира. Учитывая побочные эффекты от лекарств, лучше сбросить лишний вес или заняться физической активностью, но то, что они для многих людей работают, это факт.
"If you thought that science was certain - well, that is just an error on your part." Richard Feynman
